Run Python scripts with uv including inline dependencies (PEP 723), temporary dependencies (--with), and ephemeral tool execution. Use when running scripts, needing one-off dependencies, or creating executable Python scripts. No venv activation required.
View on GitHublaurigates/claude-plugins
python-plugin
January 24, 2026
Select agents to install to:
npx add-skill https://github.com/laurigates/claude-plugins/blob/main/python-plugin/skills/uv-run/SKILL.md -a claude-code --skill uv-runInstallation paths:
.claude/skills/uv-run/# UV Run
Run Python scripts with uv - no manual venv activation needed.
## Core Capabilities
- **Direct execution**: `uv run script.py` handles environment automatically
- **Temporary dependencies**: `uv run --with requests script.py` for one-off needs
- **Inline dependencies**: PEP 723 metadata blocks for self-contained scripts
- **Ephemeral tools**: `uvx tool` runs CLI tools without installation
## Essential Commands
### Running Scripts
```bash
# Run script (uv manages environment automatically)
uv run script.py
# Run with arguments
uv run script.py --input data.csv --output results.json
# Run a specific module
uv run -m http.server 8000
# Run with specific Python version
uv run --python 3.12 script.py
```
### Temporary Dependencies
Add dependencies for a single run without modifying project:
```bash
# Single dependency
uv run --with requests fetch_data.py
# Multiple dependencies
uv run --with requests --with rich api_client.py
# Version constraints
uv run --with 'requests>=2.31' --with 'rich>12,<14' script.py
# Combine with project dependencies
uv run --with pytest-benchmark pytest # Add benchmark to existing pytest
```
### Inline Script Dependencies (PEP 723)
Create self-contained scripts with embedded dependencies:
```python
#!/usr/bin/env -S uv run --script
# /// script
# requires-python = ">=3.11"
# dependencies = [
# "requests>=2.31",
# "rich>=13.0",
# ]
# ///
import requests
from rich import print
response = requests.get("https://api.github.com")
print(response.json())
```
Run directly:
```bash
uv run script.py
# Or make executable:
chmod +x script.py
./script.py
```
### Managing Script Dependencies
```bash
# Initialize script with metadata
uv init --script example.py --python 3.12
# Add dependency to script
uv add --script example.py requests rich
# Lock script dependencies for reproducibility
uv lock --script example.py
```
### Ephemeral Tool Execution (uvx)
Run CLI tools without installation:
```bash
# Run tool once
uvx