synthesis-matrix

# Evidence Synthesis Matrix Skill

## Purpose
Organize and synthesize evidence across multiple studies using structured matrices.

## Matrix Structure

| Study | Population | Design | Intervention | Outcome | Effect Size | Quality |
|-------|-----------|---------|--------------|---------|------------|---------|
| Smith 2023 | N=120, Adults | RCT | CBT vs WL | Depression | d=0.65 | Low RoB |
| Jones 2022 | N=85, Adolescents | RCT | CBT vs TAU | Depression | d=0.42 | Some concerns |

## Key Elements

**Study Characteristics:**
- Author, year
- Sample size
- Population details

**Methods:**
- Study design
- Intervention details
- Comparison group
- Follow-up duration

**Results:**
- Primary outcomes
- Effect sizes with CI
- Statistical significance

**Quality:**
- Risk of bias assessment
- GRADE rating
- Limitations

## Integration with Agents

Use with literature-reviewer agent to automatically populate matrices from extracted data.

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**Version:** 1.0.0