Claude Skills
CollectionsCompareWorkflowsNominate
Sign inSign up
© 2026 Curated Agent Skills·Learn more about Agent Skills
Back to repository

scientific-problem-selection

verified

This skill should be used when scientists need help with research problem selection, project ideation, troubleshooting stuck projects, or strategic scientific decisions. Use this skill when users ask to pitch a new research idea, work through a project problem, evaluate project risks, plan research strategy, navigate decision trees, or get help choosing what scientific problem to work on. Typical requests include "I have an idea for a project", "I'm stuck on my research", "help me evaluate this project", "what should I work on", or "I need strategic advice about my research".

View on GitHub

Marketplace

knowledge-work-plugins

anthropics/knowledge-work-plugins

Plugin

bio-research

Repository
Verified Org

anthropics/knowledge-work-plugins
2.8kstars

bio-research/skills/scientific-problem-selection/SKILL.md

Last Verified

February 2, 2026

Install Skill

Select agents to install to:

Scope:
npx add-skill https://github.com/anthropics/knowledge-work-plugins/blob/main/bio-research/skills/scientific-problem-selection/SKILL.md -a claude-code --skill scientific-problem-selection

Installation paths:

Claude
.claude/skills/scientific-problem-selection/
Powered by add-skill CLI

Instructions

# Scientific Problem Selection Skills

A conversational framework for systematic scientific problem selection based on Fischbach & Walsh's "Problem choice and decision trees in science and engineering" (Cell, 2024).

## Getting Started

Present users with three entry points:

**1) Pitch an idea for a new project** — to work it up together

**2) Share a problem in a current project** — to troubleshoot together

**3) Ask a strategic question** — to navigate the decision tree together

This conversational entry meets scientists where they are and establishes a collaborative tone.

---

## Option 1: Pitch an Idea

### Initial Prompt
Ask: **"Tell me the short version of your idea (1-2 sentences)."**

### Response Approach
After the user shares their idea, return a quick summary (no more than one paragraph) demonstrating understanding. Note the general area of research and rephrase the idea in a way that highlights its kernel—showing alignment and readiness to dive into details.

### Follow-up Prompt
Then ask for more detail: "Now give me a bit more detail. You might include, however briefly or even say where you are unsure:
1. What exactly you want to do
2. How you currently plan to do it
3. If it works, why will it be a big deal
4. What you think are the major risks"

### Workflow
From there, guide the user through the early stages of problem selection and evaluation:
- **Skill 1: Intuition Pumps** - Refine and strengthen the idea
- **Skill 2: Risk Assessment** - Identify and manage project risks
- **Skill 3: Optimization Function** - Define success metrics
- **Skill 4: Parameter Strategy** - Determine what to fix vs. keep flexible

See `references/01-intuition-pumps.md`, `references/02-risk-assessment.md`, `references/03-optimization-function.md`, and `references/04-parameter-strategy.md` for detailed guidance.

---

## Option 2: Troubleshoot a Problem

### Initial Prompt
Ask: **"Tell me a short version of your problem (1-2 sentences or whatever is easy)."**

### Respo

Validation Details

Front Matter
Required Fields
Valid Name Format
Valid Description
Has Sections
Allowed Tools
Instruction Length:
10304 chars