Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
View on GitHubJanuary 23, 2026
Select agents to install to:
npx add-skill https://github.com/K-Dense-AI/claude-scientific-skills/blob/cd537c1af6731965817eed2ae32b8dd8ea9d0b5e/scientific-skills/adaptyv/SKILL.md -a claude-code --skill adaptyvInstallation paths:
.claude/skills/adaptyv/# Adaptyv
Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or web interface and receive experimental results in approximately 21 days.
## Quick Start
### Authentication Setup
Adaptyv requires API authentication. Set up your credentials:
1. Contact support@adaptyvbio.com to request API access (platform is in alpha/beta)
2. Receive your API access token
3. Set environment variable:
```bash
export ADAPTYV_API_KEY="your_api_key_here"
```
Or create a `.env` file:
```
ADAPTYV_API_KEY=your_api_key_here
```
### Installation
Install the required package using uv:
```bash
uv pip install requests python-dotenv
```
### Basic Usage
Submit protein sequences for testing:
```python
import os
import requests
from dotenv import load_dotenv
load_dotenv()
api_key = os.getenv("ADAPTYV_API_KEY")
base_url = "https://kq5jp7qj7wdqklhsxmovkzn4l40obksv.lambda-url.eu-central-1.on.aws"
headers = {
"Authorization": f"Bearer {api_key}",
"Content-Type": "application/json"
}
# Submit experiment
response = requests.post(
f"{base_url}/experiments",
headers=headers,
json={
"sequences": ">protein1\nMKVLWALLGLLGAA...",
"experiment_type": "binding",
"webhook_url": "https://your-webhook.com/callback"
}
)
experiment_id = response.json()["experiment_id"]
```
## Available Experiment Types
Adaptyv supports multiple assay types:
- **Binding assays** - Test protein-target interactions using biolayer interferometry
- **Expression testing** - Measure protein expression levels
- **Thermostability** - Characterize protein thermal stability
- **Enzyme activity** - Assess enzymatic function
See `reference/experiments.md` for detailed information on each experiment type and workflows.
## Protein Sequence Optimization
Before submitting sequences, optimize them for better expression and stability:
**Common issues to address:**
- Unpaired cysteines that create unwaIssues Found: